I got past the first screen. Basically I just babbled with the other characters, watched the funny pictures of people when they talk, figured out how to save the game, and got to the next screen. It took me a while and I had to talk to multiple people, etc. After I realized the game was going to be like this the whole way, I quit. Its no good if I don't understand a bit of whats going on!
Note: It is absolutely NOTHING like the Genesis Shadowrun, which is a great game. Shadowrun for Genesis is a kick-ass action-rpg set in a futuristic world with magic and technology coexisting. I also like the novels, but apparently after FASA went under, some stupid company called Wizkids now owns the Shadowrun license and has been sitting on it. They should sell it if they are just going to let it go to waste, I would love more books and/or a new game.