bin region conversion

Hi, is it possible to use either two of the sega cd region change tools to change the BIN image of a game? I converted the BIN to ISO in cdmage, changed its region, then converted it back to BIN again and finally burnt it. However the game in question still wont boot on the real system (heart of the alien), i've now tryed iso-mp3 combinations, and bin-cue combinations of burning this game and not once will it get past the sonic splash screen. However my copies of it will play with Gens perfectly. I am beginning to suspect that the region change tools are intefering with the boot code? Has anyone ever succesfully converted a USA Heart of the Alien or Lunar, to a PAL image and played on a real system?? Or is there a way to change the region of a BIN image without converting to an ISO??
 
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