It's hurting everyone all over. Pay attention to prices at the grocery store, they're going up. It takes gas to get the food to the market. UPS and FedEx are expected to raise their prices AGAIN. Plus, non-essential items won't be selling. People can't afford to buy junk items when they don't have any disposable income left after filling the gas tank.
It cost me $50 to fill my car's 12 gallon tank today. I'm currently on unemployment. I can't afford the gas necessary to go out and look for a job but one day a week now. I have to list everyplace that's put an ad in the paper during the last week that I want to go to, then map out my route to use the least amount of gas. I also have to skip some places, if they're too far out of the way for that week's route. Hopefully they're still taking apps the following week when I can go that direction. (Thankfully, most of the jobs I've applied to I've been able to do so online. But many won't pay attention to any apps that weren't filled out on-site.)
Also, I'm somewhat convinced that the downturn in movie ticket sales that the studios keep lamenting is partialy to blame on gas prices. You can pick up some DVD rentals on your way home from work or the grocery store or whatever. Then you don't have to leave again, using more gas to get to the theaters.
On the other hand, it'll be good for the environment. That's the ONLY thing that'll benifit from people not being able to afford to drive anywhere.